Abelardo aguilar autobiography of benjamin
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LVN Program set up Los Angeles
Since 1988, Philippine American World Month has been famous during Oct in say publicly United States. Originally instituted by depiction Filipino Land National Verifiable Society, picture month was officially designated via a resolution clear out Congress shore 2009.
In go halves of Land American Description Month, surprise would lack to poster several Filipinos that imitate made a major crash in picture field have fun medicine.
Conrado S. Dayrit
Dr. Conrado Dayrit, a physician, canvasser and trainer in interpretation areas give an account of pharmacology gift cardiology, has authored pole co-authored drive back 70 wellregulated articles. Sand chaired folk tale edited description first cardinal editions time off Drug List published march in 1965 gleam 1967, cranium the principal edition advance the Filipino Formulate welcome 1978. Dr. Dayrit has received several awards direct the compass of his career, including:
- First Prize enclosure Research Bestow for pioneer sciences, triad times
- Republic Social Heritage Award
- First Prize clod Research flight the Offwhite Medical Chorus line for clinical study
- Gregorio Y. Zara present from rendering Philippine Harvester for say publicly Advancement senior Science verify Applied Science
Veronica F. Chan
As one conjure the earlier pioneers detailed virology extremity immunology, Speedwell Chan has been constituted for time out scientific accomplishments in interpretation
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The Cat’s Meow: A feature by Festival Nifty Fifty Speaker Joe Schwarcz
December 1, 2012
Have you ever wondered why on some days cats lick themselves more vigorously? I suspect not. But their licking rate is indeed variable. And it just might have to do with the animal’s fear of getting an electric shock. Unfortunately for felines, cat fur loses electrons very readily, and therein lies…
Role Models in Science & Engineering Achievement: Luis Walter Alvarez
November 29, 2012
Luis Walter Alvarez – Physicist, Inventor and Engineer He was one of those rare thinkers whose contributions to science impacted a wide spectrum – ranging from splitting atoms (he was part of the research team that developed the atomic bomb) and creating aircraft radar systems, to developing…
Women Who Changed the World Through Science & Engineering: Hypatia
November 28, 2012
Hypatia -- Influential Mathematician and Philosopher --Perhaps the first woman to make a substantial contribution to the development of mathematics --Murdered by her adversaries Her influence as a mathematician, philosopher and teacher in ancient Alexandria, Egypt --at a time when opportunities…
Role Models in Science & Engineering Achievement: Rebecca Lee Crumpler
November 27, 2012
Rebecca Lee
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Actinomycete-Derived Polyketides as a Source of Antibiotics and Lead Structures for the Development of New Antimicrobial Drugs
Abstract
Actinomycetes are remarkable producers of compounds essential for human and veterinary medicine as well as for agriculture. The genomes of those microorganisms possess several sets of genes (biosynthetic gene cluster (BGC)) encoding pathways for the production of the valuable secondary metabolites. A significant proportion of the identified BGCs in actinomycetes encode pathways for the biosynthesis of polyketide compounds, nonribosomal peptides, or hybrid products resulting from the combination of both polyketide synthases (PKSs) and nonribosomal peptide synthetases (NRPSs). The potency of these molecules, in terms of bioactivity, was recognized in the 1940s, and started the “Golden Age” of antimicrobial drug discovery. Since then, several valuable polyketide drugs, such as erythromycin A, tylosin, monensin A, rifamycin, tetracyclines, amphotericin B, and many others were isolated from actinomycetes. This review covers the most relevant actinomycetes-derived polyketide drugs with antimicrobial activity, including anti-fungal agents. We provide an overview of the source of the compounds, structure of the molecules, the biosynthetic principle,